Description

6-Azido-6-Deoxy-D-Mannose is a chemically modified monosaccharide derivative, specifically a mannose sugar functionalized with an azido group at the 6-position. This compound matters as a versatile and valuable bioorthogonal chemical building block, enabling selective conjugation and labeling in complex biological systems without interfering with native biochemical processes. It is primarily needed by researchers and manufacturers in pharmaceutical development, chemical biology, and glycobiology for applications such as metabolic glycan engineering, probe synthesis, and the development of novel therapeutics and diagnostics.

Application

• Metabolic Glycan Engineering (MGE): Used as a metabolic precursor for incorporating azide tags into cell surface glycans, enabling subsequent bioorthogonal labeling via click chemistry (e.g., CuAAC, SPAAC).
• Chemical Biology Probe Synthesis: Serves as a key intermediate for synthesizing activity-based probes, imaging agents, and affinity tags to study glycosylation pathways and carbohydrate-protein interactions.
• Glycoconjugate and Vaccine Development: Employed in the chemoenzymatic or chemical synthesis of novel glycoconjugates, including potential carbohydrate-based vaccines and immunotherapies.
• Material Science and Surface Functionalization: Facilitates the creation of azide-functionalized surfaces, hydrogels, and polymers for biomaterial development and tissue engineering applications.
• Drug Discovery: Acts as a scaffold or intermediate in the synthesis of glycosidase inhibitors, antiviral agents, and other therapeutic candidates targeting carbohydrate-mediated processes.
• Diagnostic Reagent Manufacturing: Used to produce labeled sugars and standards for analytical techniques like HPLC, MS, and NMR in diagnostic assay development.

Basic Information

Product Name	6-Azido-6-Deoxy-D-Mannose
CAS No.	316379-15-4
Molecular Formula	C6H11N3O5
Molecular Weight	205.17 g/mol
Synonyms	6-Azido-6-deoxy-D-mannopyranose; 6-Azido-6-deoxy-mannose; 6-Azidomannose; D-Mannose, 6-azido-6-deoxy-; 6-Azido-6-desoxy-D-mannose; 6-N3-D-Man; Azidomannose; 6-Deoxy-6-azido-D-mannose
EINECS	Contact for details

Quality Control

Our 6-Azido-6-Deoxy-D-Mannose is produced under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, critical for research and development applications. Quality is verified using techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is easily oxidized; for long-term storage, consider under an inert atmosphere. Keep container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.