Description

2-(Piperidin-4-Yl)-1,5,6,7-Tetrahydro-1,8-Naphthyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new APIs, particularly those with naphthyridine-based structures.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional laboratories for chemical biology studies and the development of new synthetic methodologies.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(Piperidin-4-Yl)-1,5,6,7-Tetrahydro-1,8-Naphthyridine
CAS No.	315240-28-9
Molecular Formula	C13H19N3
Molecular Weight	217.31 g/mol
Synonyms	1,5,6,7-Tetrahydro-2-(4-piperidinyl)-1,8-naphthyridine; 2-(4-Piperidinyl)-1,5,6,7-tetrahydro-1,8-naphthyridine; 4-(1,8-Naphthyridin-2-yl)piperidine (hydrogenated form); 315240-28-9; Tetrahydro-naphthyridine piperidine derivative
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-4-Yl)-1,5,6,7-Tetrahydro-1,8-Naphthyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.