Description

5-Bromo-4-Fluoro-2-Methoxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, making it a versatile intermediate for constructing complex molecular architectures. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzoate or benzamide cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and methoxy substituents.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials due to its aromatic and halogenated structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex aromatic fragments.
• Chemical Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methoxy-Benzoic Acid Methyl Ester
CAS No.	314298-22-1
Molecular Formula	C9H8BrFO3
Molecular Weight	263.06 g/mol
Synonyms	Methyl 5-Bromo-4-Fluoro-2-Methoxybenzoate; 2-Methoxy-5-bromo-4-fluorobenzoic Acid Methyl Ester; Benzoic acid, 5-bromo-4-fluoro-2-methoxy-, methyl ester; 5-Bromo-4-fluoro-2-methoxybenzoic acid methyl ester; Methyl 5-bromo-4-fluoro-2-methoxybenzoate; 314298-22-1; 5-Br-4-F-2-MeO-BA-Me
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Methoxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.