Description

1,3-Benzenedicarboxylic Acid,5-[(2-Thienylcarbonyl)Amino]-,Dimethyl Ester is a specialized organic intermediate featuring a thiophene-based amide linkage on an isophthalate diester backbone. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique molecular architecture imparts specific electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex heterocyclic systems and functional monomers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, or insecticides with enhanced efficacy and selectivity.
• Functional Polymer Monomer: Used in the production of specialty polyamides, polyimides, or coatings that require specific thermal stability, solubility, or optical properties derived from the thiophene moiety.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating novel chelating ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors, photovoltaic materials, or electrochromic devices due to its conjugated system.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex heterocyclic dyes with specific color fastness and application properties.

Basic Information

Product Name	1,3-Benzenedicarboxylic Acid,5-[(2-Thienylcarbonyl)Amino]-,Dimethyl Ester
CAS No.	314284-47-4
Molecular Formula	C16H13NO5S
Molecular Weight	331.34 g/mol
Synonyms	Dimethyl 5-[(thiophene-2-carbonyl)amino]isophthalate; 5-[(2-Thienylcarbonyl)amino]isophthalic Acid Dimethyl Ester; 5-(Thiophene-2-carboxamido)isophthalic Acid Dimethyl Ester; 1,3-Benzenedicarboxylic acid, 5-[(2-thienylcarbonyl)amino]-, 1,3-dimethyl ester; Dimethyl 5-(2-thiophenecarboxamido)isophthalate; CAS 314284-47-4
EINECS	Contact for details

Quality Control

Our production of 1,3-Benzenedicarboxylic Acid,5-[(2-Thienylcarbonyl)Amino]-,Dimethyl Ester adheres to a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as assay, related substances, and residual solvents are available upon request. We support development and commercial projects with material produced under current Good Manufacturing Practice (cGMP) principles where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.