Description

2,4,6-Tri-o-Acetyl-3-o-Benzyl-β-D-Glucopyranosyl Trichloroacetimidate is a high-purity, advanced glycosyl donor extensively used in stereoselective glycosylation reactions. This compound is critical for the efficient synthesis of complex oligosaccharides and glycoconjugates, offering excellent reactivity and selectivity under mild conditions. It is an essential building block for researchers and manufacturers in pharmaceutical development, particularly for creating novel carbohydrate-based drugs, vaccines, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycobiology Research: Essential reagent for the chemical and enzymatic synthesis of defined oligosaccharides and glycans for structure-activity relationship studies.
• Vaccine Development: Used in the construction of synthetic carbohydrate antigens for conjugate vaccine candidates against bacterial and viral pathogens.
• Glycoconjugate Synthesis: Enables the attachment of carbohydrate moieties to proteins, lipids, or other scaffolds to create mimics of natural glycostructures.
• Process Chemistry: Employed in scalable routes for the production of glycosylated natural products and therapeutic agents.
• Diagnostic Reagent Manufacturing: Serves as a precursor for labeled glycans used in diagnostic assays and imaging probes.

Basic Information

Product Name	2,4,6-Tri-o-Acetyl-3-o-Benzyl-β-D-Glucopyranosyl Trichloroacetimidate
CAS No.	314038-30-7
Molecular Formula	C₂₂H₂₆Cl₃NO₉
Molecular Weight	562.80 g/mol
Synonyms	3-O-Benzyl-2,4,6-tri-O-acetyl-β-D-glucopyranosyl trichloroacetimidate; 2,4,6-Tri-O-acetyl-3-O-benzyl-β-D-glucopyranosyl trichloroacetimidate; β-D-Glucopyranosyl trichloroacetimidate, 3-O-benzyl-2,4,6-tri-O-acetyl-; Glucosyl Donor, Acetylated Benzyl Protected; Trichloroacetimidate Glycosylation Reagent; TCAI Glycosyl Donor
EINECS	Contact for details

Quality Control

Every batch of 2,4,6-Tri-o-Acetyl-3-o-Benzyl-β-D-Glucopyranosyl Trichloroacetimidate is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products meet high standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.