Description

Methyl2-(Bromomethyl)-3-Iodobenzoate is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its dual reactive sites, the bromomethyl and iodo groups, which enable sequential and selective cross-coupling reactions. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring selective halogenation for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where the benzoate scaffold is integral.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings via the iodo group, followed by further modification of the bromomethyl group.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules or affinity probes for studying biological pathways and target identification.

Basic Information

Product Name	Methyl2-(Bromomethyl)-3-Iodobenzoate
CAS No.	312747-81-2
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Methyl 2-(Bromomethyl)-3-iodobenzoate; 3-Iodo-2-(bromomethyl)benzoic Acid Methyl Ester; Benzoic acid, 2-(bromomethyl)-3-iodo-, methyl ester; Methyl 3-iodo-2-(bromomethyl)benzoate; 2-(Bromomethyl)-3-iodobenzoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl2-(Bromomethyl)-3-Iodobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.