Description

Spiro[2.2]Pentanecarboxylic Acid, 1-Methyl-4-Methylene-, Methyl Ester (9Ci) is a specialized spirocyclic organic ester, a high-value building block in advanced chemical synthesis. Its unique constrained spiro[2.2]pentane framework and reactive methylene group make it a critical intermediate for developing novel materials and pharmaceuticals. This compound is essential for R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries seeking to incorporate rigid, three-dimensional structural motifs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, spirocyclic cores to modulate biological activity and improve metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents, where its unique structure can contribute to new modes of action and enhanced environmental profiles.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Fine Chemical Building Block: Provides a versatile starting point for the synthesis of complex natural product analogs and other high-value specialty chemicals.

Basic Information

Product Name	Spiro[2.2]Pentanecarboxylic Acid, 1-Methyl-4-Methylene-, Methyl Ester (9Ci)
CAS No.	312738-22-0
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	1-Methyl-4-methylenespiro[2.2]pentane-1-carboxylic acid methyl ester; Methyl 1-methyl-4-methylenespiro[2.2]pentane-1-carboxylate; Spiro[2.2]pentane-1-carboxylic acid, 1-methyl-4-methylene-, methyl ester; 1-Methyl-4-methylenespiro[2.2]pentyl-1-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Spiro[2.2]Pentanecarboxylic Acid, 1-Methyl-4-Methylene-, Methyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.