Description

3 4-Di-o-Acetyl-6-o-(Triisopropylsilyl) is a key protected carbohydrate intermediate, specifically a silyl-protected acetylated sugar derivative. This compound is essential for its role in multi-step organic synthesis, where it provides selective protection for hydroxyl groups, enabling precise chemical transformations. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules, including nucleosides and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Oligonucleotide Synthesis: Used in the preparation of protected nucleoside phosphoramidites for solid-phase DNA/RNA synthesis.
• Glycochemistry Research: Serves as a versatile precursor for the controlled synthesis of complex carbohydrates and glycoconjugates.
• Process Chemistry: Enables scalable, selective protection strategies in the development of efficient manufacturing routes for fine chemicals.
• Agrochemical Development: Employed in the research and synthesis of new sugar-based pesticide and herbicide candidates.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	3 4-Di-o-Acetyl-6-o-(Triisopropylsilyl)
CAS No.	312692-92-5
Molecular Formula	C20H38O7Si
Molecular Weight	418.60 g/mol
Synonyms	1,2-Di-O-acetyl-3,5-di-O-benzyl-6-O-(triisopropylsilyl)-D-glucofuranose; 6-O-Triisopropylsilyl-1,2-di-O-acetyl-3,5-di-O-benzyl-D-glucofuranose; TIPS-protected acetylated glucofuranose derivative; 3,5-Di-O-benzyl-1,2-di-O-acetyl-6-O-triisopropylsilyl-D-glucofuranose; 1,2-Di-O-acetyl-3,5-di-O-benzyl-6-O-(triisopropylsilyl)-α/β-D-glucofuranose; Protected D-glucofuranose intermediate; TIPS-glucofuranose diacetate
EINECS	Contact for details

Quality Control

Our 3 4-Di-o-Acetyl-6-o-(Triisopropylsilyl) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.