Description

2-Amino-8-Pyridin-3-Yl-7,9-Dioxa-1-Thia-3-Aza-Spiro[4.5]Dec-2-En-4-One is a sophisticated spirocyclic heterocyclic compound featuring a unique molecular architecture that combines pyridine, dioxa, and thia-aza ring systems. This complex structure makes it a highly valuable intermediate for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in cutting-edge medicinal chemistry and agrochemical discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Agrochemical Development: Serves as a precursor for creating new pesticides and herbicides with novel modes of action.
• Ligand Synthesis: Potential use in constructing complex chelating agents or catalysts for asymmetric synthesis.
• Material Science: Exploration into organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, multi-heteroatom structure.

Basic Information

Product Name	2-Amino-8-Pyridin-3-Yl-7,9-Dioxa-1-Thia-3-Aza-Spiro[4.5]Dec-2-En-4-One
CAS No.	312608-26-7
Molecular Formula	C14H14N4O3S
Molecular Weight	318.35 g/mol
Synonyms	2-Amino-8-(3-pyridinyl)-7,9-dioxa-1-thia-3-azaspiro[4.5]dec-2-ene-4-one; 2-Amino-8-(pyridin-3-yl)-7,9-dioxa-1-thia-3-aza-spiro[4.5]dec-2-en-4-one; 312608-26-7; Spiro[4.5]dec-2-ene-4-one, 2-amino-8-(3-pyridinyl)-7,9-dioxa-1-thia-3-aza-; 3-Pyridinepropanamide, γ-lactone derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet exacting customer specifications, with purity typically exceeding 97% (HPLC). Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom synthesis under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.