Description

Carbamic Acid, [(2S,3E)-2-Hydroxy-3-Pentenyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel therapeutics, particularly in the areas of enzyme inhibitors and chiral active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Asymmetric Synthesis: Utilized in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Peptidomimetic Research: Serves as a building block for designing and synthesizing peptide analogs and mimetics with enhanced metabolic stability.
• Agrochemical Development: Used in the research and development of advanced, chiral active ingredients for crop protection products.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry research for probing biological pathways and structure-activity relationships (SAR).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	Carbamic Acid, [(2S,3E)-2-Hydroxy-3-Pentenyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	312521-40-7
Molecular Formula	C10H19NO3
Molecular Weight	201.26 g/mol
Synonyms	tert-Butyl N-[(2S,3E)-2-hydroxy-3-penten-1-yl]carbamate; (2S,3E)-2-Hydroxy-3-penten-1-yl tert-butylcarbamate; (2S,3E)-2-Hydroxy-3-pentenylcarbamic acid tert-butyl ester; N-Boc-(2S,3E)-2-Hydroxy-3-pentenylamine; Boc-L-2-Hydroxy-3-pentenylamine; tert-Butyl ((2S,3E)-2-hydroxy-3-pentenyl)carbamate
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, [(2S,3E)-2-Hydroxy-3-Pentenyl]-, 1,1-Dimethylethyl Ester (9Ci) adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure compliance with exacting R&D and cGMP-grade standards where applicable. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.