Description

L-Threo-Hexonic Acid, 2,4-Dideoxy-3-o-Methyl-, δ-Lactone (9Ci) is a specialized chiral building block and intermediate of significant interest in advanced organic synthesis. Its unique stereochemistry and lactone functionality make it a valuable precursor for the development of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers engaged in the synthesis of nucleoside analogs, carbohydrate-based drugs, and other fine chemicals requiring precise stereocontrol.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel antiviral and anticancer agents, particularly nucleoside analogs.
• Carbohydrate Chemistry Research: Used in academic and industrial R&D to study glycosylation reactions and to synthesize complex sugar derivatives and mimics.
• Fine Chemical Synthesis: Serves as a building block for creating specialty chemicals, flavors, and fragrances that require specific stereochemistry.
• Bioconjugate Chemistry: Potential use in the synthesis of labeled compounds or prodrugs where its functional groups can be selectively modified.
• Agrochemical Development: Intermediate in the synthesis of advanced, biologically active compounds with specific stereochemical requirements.

Basic Information

Product Name	L-Threo-Hexonic Acid, 2,4-Dideoxy-3-o-Methyl-, δ-Lactone (9Ci)
CAS No.	310883-86-4
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	2,4-Dideoxy-3-O-methyl-L-threo-hexono-1,5-lactone; 3-O-Methyl-2,4-dideoxy-L-threo-hexono-1,5-lactone; L-threo-Hexonic acid, 2,4-dideoxy-3-O-methyl-, δ-lactone; (3S,5R)-3-Hydroxy-5-(hydroxymethyl)-4-methoxydihydrofuran-2(3H)-one; A chiral deoxy sugar lactone intermediate.
EINECS	Contact for details

Quality Control

Our L-Threo-Hexonic Acid, 2,4-Dideoxy-3-o-Methyl-, δ-Lactone (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and IR spectroscopy, to ensure it meets the exacting standards required for research and pharmaceutical development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.