Description

tert-Butyl (S)-2-(2-Ethoxy-2-Oxoethyl)Piperidine-1-Carboxylate is a high-value, chiral piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry and functional groups enable precise molecular construction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Agrochemical Research: Employed in the development of novel, optically active pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts.
• Peptidomimetics: Incorporated into the design of peptide-like molecules to enhance stability and bioavailability.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploratory chemistry in process chemistry.

Basic Information

Product Name	tert-Butyl (S)-2-(2-Ethoxy-2-Oxoethyl)Piperidine-1-Carboxylate
CAS No.	308273-64-5
Molecular Formula	C14H25NO4
Molecular Weight	271.35 g/mol
Synonyms	1-Boc-2-(2-ethoxy-2-oxoethyl)-(S)-piperidine; (S)-1-tert-Butyl 2-ethyl 1,2-piperidinedicarboxylate; (S)-tert-Butyl 2-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate; (S)-1-(tert-Butoxycarbonyl)-2-(ethoxycarbonylmethyl)piperidine; (S)-N-Boc-2-(ethoxycarbonylmethyl)piperidine; (S)-2-(Ethoxycarbonylmethyl)-1-(tert-butoxycarbonyl)piperidine; (S)-1-Boc-piperidine-2-acetic acid ethyl ester; 308273-64-5
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (S)-2-(2-Ethoxy-2-Oxoethyl)Piperidine-1-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, enantiomeric excess, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.