Description

3 6-Di-o-(tert-Butyldiphenylsilyl)-D- is a high-purity, protected carbohydrate derivative, specifically a silyl-protected D-galactose derivative, widely used as a critical chiral building block in organic synthesis. Its primary value lies in providing precise stereochemical control and robust protection for hydroxyl groups during complex multi-step reactions, enabling the synthesis of sophisticated bioactive molecules. This compound is essential for researchers and process chemists in the pharmaceutical and fine chemical industries, particularly for developing nucleoside analogs, antiviral agents, and other glycosylated therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of nucleoside analogs and antiviral drugs.
• Glycochemistry Research: Used in the study and synthesis of complex oligosaccharides and glycoconjugates.
• Protecting Group Strategy: The tert-butyldiphenylsilyl (TBDPS) groups provide orthogonal protection for specific hydroxyl positions in carbohydrate chemistry.
• Process Chemistry: Serves as a reliable, high-purity starting material for scalable GMP production of active pharmaceutical ingredients (APIs).
• Chemical Biology: Utilized in the preparation of labeled sugar derivatives for metabolic pathway studies and probe development.

Basic Information

Product Name	3 6-Di-o-(tert-Butyldiphenylsilyl)-D-
CAS No.	308103-43-7
Molecular Formula	C40H54O5Si2
Molecular Weight	671.03 g/mol
Synonyms	1,2:5,6-Di-O-(tert-Butyldiphenylsilyl)-α-D-galactofuranose; 1,2:5,6-Di-O-(TBDPS)-α-D-galactofuranose; 3,6-Di-O-(tert-butyldiphenylsilyl)-D-galactose derivative; Di-TBDPS-D-galactofuranose; α-D-Galactofuranose 1,2:5,6-bis-O-(tert-butyldiphenylsilyl) ether; TBDPS-protected D-galactose
EINECS	Contact for details

Quality Control

Our 3 6-Di-o-(tert-Butyldiphenylsilyl)-D- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and GMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, ensuring the material meets the stringent requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.