Description

5-Methyl-2-(trifluoromethyl)-3-furyl isocyanate is a specialized, high-value heterocyclic isocyanate building block. This compound is critical for introducing the unique 5-methyl-2-(trifluoromethyl)furan-3-yl moiety into target molecules, offering enhanced lipophilicity and metabolic stability. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique surface properties or chemical resistance.
• Chemical Biology Probes: Employed to create isocyanate-reactive probes for labeling proteins or other biomolecules to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke organic compounds for client-specific applications.

Basic Information

Product Name	5-Methyl-2-(Trifluoromethyl)-3-Furyl Isocyanate
CAS No.	306935-03-5
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	3-Furylisocyanate, 5-methyl-2-(trifluoromethyl)-; 5-Methyl-2-(trifluoromethyl)furan-3-isocyanate; 2-(Trifluoromethyl)-5-methyl-3-furyl isocyanate; 5-Methyl-2-trifluoromethyl-3-furyl isocyanate; 3-Isocyanato-5-methyl-2-(trifluoromethyl)furan; CAS 306935-03-5
EINECS	Contact for details

Quality Control

Every batch of 5-Methyl-2-(trifluoromethyl)-3-furyl isocyanate is manufactured and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.