Description

3-Methanesulfonylaminophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the synthesis of novel active ingredients. The CAS number for this compound is provided in the table below.

Application

• Pharmaceutical Intermediates: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific phenylboronate motifs.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and sensors.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the development of chemical probes and PROTACs.
• Catalyst & Ligand Development: Serves as a starting material for creating novel palladium ligands and organocatalysts.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates under cGMP conditions where applicable.

Basic Information

Product Name	3-Methanesulfonylaminophenylboronic Acid, Pinacol Ester
CAS No.	305448-92-4
Molecular Formula	C14H22BNO4S
Molecular Weight	311.21 g/mol
Synonyms	3-[(Methanesulfonyl)amino]benzeneboronic Acid Pinacol Ester; 3-(Methylsulfonamido)phenylboronic Acid Pinacol Ester; N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide; B-(3-[(Methylsulfonyl)amino]phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methanesulfonamidophenylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3-Methanesulfonylaminophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with various pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0% (by NMR)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.