Description

α-(4-Chlorophenyl)-2-Methyl-n-2-Pyridinyl-1H-Indole-3-Methanamine CAS NO 305372-78-5 is a high-purity, complex heterocyclic organic compound featuring a unique indole-pyridine core structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical building block for the development of novel active molecules. It is essential for R&D chemists and process developers in the pharmaceutical, agrochemical, and life science sectors seeking to synthesize new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pest management products.
• Chemical Biology & Medicinal Chemistry: Employed in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic pathways.
• Organic Synthesis & Process Development: Serves as a sophisticated scaffold for synthesizing complex molecules in academic and industrial research laboratories.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	α-(4-Chlorophenyl)-2-Methyl-n-2-Pyridinyl-1H-Indole-3-Methanamine
CAS No.	305372-78-5
Molecular Formula	C21H18ClN3
Molecular Weight	347.84 g/mol
Synonyms	1H-Indole-3-methanamine, α-(4-chlorophenyl)-2-methyl-N-2-pyridinyl-; 2-Methyl-N-(pyridin-2-yl)-1-[4-chlorophenyl]indol-3-yl]methanamine; 4-Chloro-α-(2-methyl-1H-indol-3-yl)-N-(2-pyridinyl)benzenemethanamine; (4-Chlorophenyl)(2-methyl-1-(pyridin-2-yl)-1H-indol-3-yl)methanamine; α-(4-Chlorophenyl)-2-methyl-N-(pyridin-2-yl)-1H-indole-3-methanamine; CAS 305372-78-5
EINECS	Contact for details

Quality Control

Our α-(4-Chlorophenyl)-2-Methyl-n-2-Pyridinyl-1H-Indole-3-Methanamine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be light-sensitive and hygroscopic; handle and store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.