Description

(+/-)-Norepinephrine L-Bitartrate CAS NO 304903-81-9 is a synthetic salt form of the critical neurotransmitter and hormone norepinephrine, offering enhanced stability for research and development applications. This compound is essential for studying adrenergic receptor mechanisms, cardiovascular physiology, and neurological pathways in preclinical models. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic reagents and reference standards.

Application

• Pharmaceutical Research & Development: A key reference standard and intermediate in the synthesis and analytical method development for cardiovascular and neurological drugs targeting adrenergic receptors.
• Biochemical & Pharmacological Studies: Used in in vitro and in vivo experiments to investigate vasoconstriction, blood pressure regulation, and the fight-or-flight response.
• Diagnostic Reagent Manufacturing: Serves as a critical raw material in the production of calibration standards and controls for clinical diagnostic assays.
• Academic & Institutional Research: Fundamental for neuroscience, physiology, and pharmacology departments studying neurotransmitter function and signal transduction.
• Quality Control & Analytical Testing: Employed as a known compound in HPLC, LC-MS, and other chromatographic systems for method validation and impurity profiling.

Basic Information

Product Name	(+/-)-Norepinephrine L-Bitartrate
CAS No.	304903-81-9
Molecular Formula	C12H17NO9 • xH2O
Molecular Weight	319.27 g/mol (anhydrous basis)
Synonyms	(±)-Norepinephrine L-Bitartrate; DL-Norepinephrine Bitartrate; Noradrenaline Bitartrate; (R*,S*)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol (R*,R*)-2,3-dihydroxybutanedioate (1:1); Arterenol Bitartrate; Levarterenol Bitartrate; Noradrenaline Acid Tartrate; 1,2-Benzenediol, 4-[(1R)-2-amino-1-hydroxyethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
EINECS	Contact for details

Quality Control

Our (+/-)-Norepinephrine L-Bitartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container should be kept sealed under an inert atmosphere after opening and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.