Description

5-Acetyl-6-Methyl-2-(4-Methylpiperazino)Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by R&D laboratories, custom synthesis firms, and pharmaceutical manufacturers engaged in developing new drug candidates, especially within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Serves as a specialized starting material for contract research organizations (CROs) and CDMOs (Contract Development and Manufacturing Organizations).
• API Manufacturing: Employed in the production scale-up of complex target molecules for preclinical and clinical trials.
• Chemical Biology: Potential use as a molecular probe or scaffold in biochemical assay development.

Basic Information

Product Name	5-Acetyl-6-Methyl-2-(4-Methylpiperazino)Nicotinonitrile
CAS No.	303147-02-6
Molecular Formula	C14H18N4O
Molecular Weight	258.32 g/mol
Synonyms	5-Acetyl-6-methyl-2-(4-methyl-1-piperazinyl)-3-pyridinecarbonitrile; 2-(4-Methylpiperazin-1-yl)-5-acetyl-6-methylnicotinonitrile; 3-Cyano-5-acetyl-6-methyl-2-(4-methylpiperazino)pyridine; 5-Acetyl-2-(4-methylpiperazino)-6-methylnicotinonitrile; Nicotinonitrile, 5-acetyl-6-methyl-2-(4-methyl-1-piperazinyl)-; 303147-02-6
EINECS	Contact for details

Quality Control

Our 5-Acetyl-6-Methyl-2-(4-Methylpiperazino)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.