Description

4-Bromo-2,6-Difluorophenyl Isocyanate is a specialized aromatic isocyanate building block, crucial for introducing a bromo-difluoro substituted phenyl moiety into advanced molecular architectures. Its primary value lies in enabling the synthesis of complex, high-value compounds where precise halogen and fluorine substitution patterns are required for specific electronic or steric properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting novel small molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the bromine and fluorine atoms enhance biological activity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for the development of specialty polyurethanes, coatings, and high-performance polymers with tailored properties.
• Ligand & Catalyst Development: Employed in the creation of novel organometallic complexes and catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science for constructing complex heterocycles and functional molecules.

Basic Information

Product Name	4-Bromo-2,6-Difluorophenyl Isocyanate
CAS No.	302912-26-1
Molecular Formula	C7H2BrF2NO
Molecular Weight	233.99 g/mol
Synonyms	2,6-Difluoro-4-bromophenyl isocyanate; 1-Bromo-3,5-difluoro-4-isocyanatobenzene; 4-Bromo-2,6-difluorophenyl isocyanate; Isocyanic acid, 4-bromo-2,6-difluorophenyl ester; 4-Bromo-2,6-difluoro-1-isocyanatobenzene; (4-Bromo-2,6-difluorophenyl)isocyanate
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from moisture, heat, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.