Description

Diethyl (2-Amino-4-Chloroanilino)Methylphosphonate Hydrochloride is a specialized organophosphorus compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which combines an aminochloroaniline moiety with a phosphonate ester group, making it a versatile intermediate for creating complex molecules. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Building block for developing new generation herbicides, pesticides, and plant growth regulators with enhanced efficacy.
• Chemical Synthesis: Versatile reagent for constructing complex molecules in medicinal chemistry and material science research.
• Ligand & Catalyst Development: Used in the preparation of specialized phosphonate-based ligands for catalytic applications.
• Bioconjugation Chemistry: Potential use in creating linkers for antibody-drug conjugates (ADCs) and other biopharmaceuticals.

Basic Information

Product Name	Diethyl (2-Amino-4-Chloroanilino)Methylphosphonate Hydrochloride
CAS No.	301822-79-7
Molecular Formula	C11H19ClN2O3P • HCl
Molecular Weight	338.62 g/mol (Free base: 302.71 g/mol)
Synonyms	Diethyl [(2-Amino-4-chlorophenyl)amino](methyl)phosphonate Hydrochloride; Phosphonic acid, [(2-amino-4-chlorophenyl)amino]methyl-, diethyl ester, hydrochloride; Diethyl (2-Amino-4-Chloroanilino)Methylphosphonate HCl; (2-Amino-4-chloroanilino)methanephosphonic acid diethyl ester hydrochloride; AE 001; AE-001; AE001; CAS 301822-79-7
EINECS	Contact for details

Quality Control

Our Diethyl (2-Amino-4-Chloroanilino)Methylphosphonate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing all critical parameters, including assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.