Description

Ent-Estradiol 17-Valerate is a high-purity enantiomer of the steroid hormone estradiol valerate, distinguished by its specific spatial configuration. This compound is of significant interest in advanced pharmaceutical research and development, particularly for studying stereospecific biological activity and receptor interactions. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require enantiomerically pure materials for method development, quality control, and novel API synthesis.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control of estradiol-based drug products.
• Steroid Research Intermediate: Serves as a key chiral building block in the synthesis of novel steroid derivatives and enantiomerically pure active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating the stereoselective binding and metabolic pathways of estrogenic compounds.
• Analytical Chemistry: Utilized as a high-purity standard in chromatographic analyses (HPLC, GC) and spectroscopic studies.
• Academic & Institutional Research: Supports fundamental research in endocrinology, pharmacology, and medicinal chemistry at universities and research institutes.

Basic Information

Product Name	Ent-Estradiol 17-Valerate
CAS No.	300853-47-8
Molecular Formula	C23H32O3
Molecular Weight	356.50 g/mol
Synonyms	17β-Estradiol 17-valerate enantiomer; (17β)-Estra-1,3,5(10)-triene-3,17-diol 17-pentanoate; Enantiomeric Estradiol Valerate; Ent-E2V; Estra-1,3,5(10)-triene-3,17β-diol 17-valerate (enantiomer); (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol 17-pentanoate
EINECS	Contact for details

Quality Control

Our Ent-Estradiol 17-Valerate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess. We support compliance with relevant pharmacopeial guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.