Description

Ethyl 1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarboxylate is a high-purity chemical intermediate of significant importance in modern pharmaceutical research and development. This compound serves as a critical building block for the synthesis of complex molecules, particularly those targeting central nervous system and other therapeutic areas. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and scale-up synthesis of potential APIs with piperidine and pyridine core structures.
• Chemical Biology Research: Employed as a scaffold or probe molecule in the study of biological targets and pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for synthetic organic chemistry and pharmacology studies.
• Process Chemistry Optimization: Serves as a standard or starting material for developing and optimizing robust synthetic routes.

Basic Information

Product Name	Ethyl 1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarboxylate
CAS No.	300804-00-6
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	Ethyl 1-(5-nitro-2-pyridyl)piperidine-4-carboxylate; 4-Piperidinecarboxylic acid, 1-(5-nitro-2-pyridinyl)-, ethyl ester; 1-(5-Nitro-2-pyridinyl)-4-piperidinecarboxylic acid ethyl ester; Ethyl 1-(5-nitropyridin-2-yl)piperidine-4-carboxylate; 5-Nitro-2-(4-(ethoxycarbonyl)piperidin-1-yl)pyridine; Ethyl 4-(5-nitro-2-pyridinyl)-1-piperidinecarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 1-(5-Nitro-2-Pyridinyl)-4-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected by the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.