Description

n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(2,4,5-Trichlorophenyl) Ester is a sophisticated, high-purity chemical intermediate designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities where structural complexity and chiral purity are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics, leveraging the protected glutamic acid moiety.
• Agrochemical Research: Serves as a building block for developing novel herbicides or plant growth regulators, utilizing the trichlorophenyl ester group.
• Chemical Biology Probes: Employed in the creation of specialized probes and linkers for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Facilitates research in medicinal chemistry and organic methodology development within university and corporate laboratories.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(2,4,5-Trichlorophenyl) Ester
CAS No.	39993-96-9
Molecular Formula	C20H18Cl3NO6
Molecular Weight	474.72 g/mol
Synonyms	Z-L-Glu(OMe)-O-2,4,5-Trichlorophenyl; (S)-5-Methoxy-5-oxo-4-((((benzyloxy)carbonyl)amino)pentanoic acid 2,4,5-trichlorophenyl ester; L-Glutamic acid, N-[(benzyloxy)carbonyl]-, 5-methyl 1-(2,4,5-trichlorophenyl) ester; Cbz-L-Glu(OMe)-O-2,4,5-Trichlorophenyl Ester; N-Carbobenzoxy-L-glutamic acid α-methyl γ-(2,4,5-trichlorophenyl) ester; Nα-Cbz-L-glutamic acid 1-methyl 5-(2,4,5-trichlorophenyl) ester; Benzyl N-[(S)-4-methoxy-4-oxo-1-[(2,4,5-trichlorophenoxy)carbonyl]butyl]carbamate
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]-L-Glutamic Acid 5-Methyl 1-(2,4,5-Trichlorophenyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.