Description

Nilestriol is a synthetic steroidal estrogen compound with significant research and pharmaceutical applications. Its specific molecular structure makes it a valuable intermediate in the synthesis of more complex hormonal agents and a reference standard in analytical chemistry. This high-purity compound is essential for pharmaceutical R&D, quality control laboratories, and academic institutions focused on endocrinology and steroid chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced steroidal drugs and hormone therapies.
• Analytical Reference Standard: Used for method development, calibration, and quality control testing in HPLC, GC, and other chromatographic systems.
• Biochemical Research: Employed in studies investigating estrogen receptor binding, hormonal pathways, and metabolic processes.
• Academic & Institutional Use: Serves as a pure compound for teaching and advanced research in university chemistry and pharmacology departments.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Nilestriol
CAS No.	39791-20-3
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	17α-Ethynylestriol; 17α-Ethynyl-1,3,5(10)-estratriene-3,16α,17β-triol; Ethynylestriol; 17α-Ethynylestra-1,3,5(10)-triene-3,16α,17β-triol; NSC 121773; Nilestriolum
EINECS	Contact for details

Quality Control

Our Nilestriol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.