Description

N-Phthaloyl-DL-Threonine Methyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled construction of complex peptide structures and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

• Peptide Synthesis: As a key intermediate for the controlled incorporation of threonine residues into peptide chains, particularly in solid-phase peptide synthesis (SPPS).
• Pharmaceutical Research: A vital building block in the research and development of new drug candidates, including protease inhibitors and other biologically active peptides.
• Chemical Biology: Used in the synthesis of modified peptides and peptidomimetics for studying protein-protein interactions and enzyme mechanisms.
• Fine Chemical Production: Serves as a chiral synthon in the multi-step synthesis of complex organic molecules requiring high stereochemical purity.
• Academic Research: Employed in university and institutional laboratories for methodological development in asymmetric synthesis and protecting group chemistry.

Basic Information

Product Name	N-Phthaloyl-DL-Threonine Methyl Ester
CAS No.	39739-08-7
Molecular Formula	C₁₄H₁₅NO₆
Molecular Weight	293.27 g/mol
Synonyms	DL-Threonine, N-phthaloyl-, methyl ester; Methyl N-phthaloyl-DL-threoninate; Phthaloyl-DL-threonine methyl ester; Methyl 2-(1,3-dioxoisoindolin-2-yl)-3-hydroxybutanoate; 2-(1,3-Dioxoisoindolin-2-yl)-3-hydroxybutanoic acid methyl ester; N-(Phthaloyl)-DL-threonine methyl ester; DL-N-Phthaloylthreonine methyl ester
EINECS	Contact for details

Quality Control

Our N-Phthaloyl-DL-Threonine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the exacting standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.