Description

(S)-(-)-2-Isocyanato-4-Methylvaleric Acid Methyl Ester CAS NO 39570-63-3 is a high-purity, chiral isocyanate derivative of a methyl valerate. This compound is a critical chiral building block for the synthesis of enantiomerically pure pharmaceuticals and advanced materials. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in protease inhibitors and other small molecule therapeutics.
• Peptide Mimetics & Conjugates: Used to introduce the isocyanate functional group for coupling reactions, enabling the creation of peptide-based drugs and diagnostic agents.
• Agrochemical Synthesis: Serves as a building block for chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry impacts biological activity.
• Polymer Modification: Employed in the production of specialty polyurethanes and polymers with tailored properties for coatings, adhesives, and elastomers.
• Chemical Biology Probes: Utilized in research to label or cross-link biomolecules for studying protein interactions and cellular pathways.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing chiral ligands used in asymmetric synthesis.

Basic Information

Product Name	(S)-(-)-2-Isocyanato-4-Methylvaleric Acid Methyl Ester
CAS No.	39570-63-3
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(S)-Methyl 2-Isocyanato-4-methylpentanoate; (S)-(-)-2-Isocyanato-4-methylvaleric acid methyl ester; Methyl (S)-2-isocyanato-4-methylpentanoate; L-Leucine, N-carboxy-, methyl ester, isocyanate; (S)-Methyl 4-methyl-2-isocyanatopentanoate; Methyl (S)-4-methyl-2-isocyanatopentanoate; (S)-2-Isocyanato-4-methylpentanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Isocyanato-4-Methylvaleric Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.