Description

4-[(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester is a specialized organosilicon compound featuring both silylated amino and carboxylic acid ester functional groups. This dual-protected derivative is crucial for synthetic chemists as a versatile building block and protecting group reagent, particularly in peptide and complex molecule synthesis. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors for introducing or masking functional groups under mild conditions.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex natural products.
• Peptide Chemistry: Used for the temporary protection of amino and carboxyl groups during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Agrochemical Synthesis: Employed as a building block in creating novel herbicides, fungicides, and plant growth regulators with tailored properties.
• Silicon-Based Material Precursor: Acts as a monomer or modifying agent in the synthesis of specialized silicones, silsesquioxanes, and other hybrid organic-inorganic materials.
• Cross-Coupling Reactions: Functions as a substrate in palladium-catalyzed and other metal-mediated cross-coupling reactions to form new carbon-carbon or carbon-heteroatom bonds.
• Derivatization Agent: Utilized in analytical chemistry to silylate sensitive compounds for Gas Chromatography (GC) or Mass Spectrometry (MS) analysis, improving volatility and detection.

Basic Information

Item	Details
Product Name	4-[(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester
CAS No.	39538-11-9
Molecular Formula	C10H25NO2Si2
Molecular Weight	247.49 g/mol
Synonyms	4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester; 4-(Trimethylsilylamino)butyric Acid Trimethylsilyl Ester; γ-[(Trimethylsilyl)amino]butyric Acid Trimethylsilyl Ester; 4-(Trimethylsilylamino)butanoic Acid Trimethylsilyl Ester; N-(Trimethylsilyl)-4-aminobutanoic Acid Trimethylsilyl Ester; TMS-4-Aminobutyrate TMS Ester; Bis(trimethylsilyl) Derivative of 4-Aminobutyric Acid
EINECS	Contact for details

Quality Control

Our production of 4-[(Trimethylsilyl)Amino]Butyric Acid Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.