Description

n-Trimethylsilylmethyl-n-Nitrosourea is a specialized organosilicon nitrosourea compound, primarily utilized as a versatile reagent in advanced organic synthesis. Its value lies in its unique dual functionality, serving as a silylating agent and a nitrosourea precursor, which enables critical transformations in the development of complex molecules. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for constructing novel molecular scaffolds and protecting group strategies.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for introducing the nitrosourea moiety in the development of potential chemotherapeutic agents and other active pharmaceutical ingredients (APIs).
• Organosilicon Chemistry: Acts as a silylating agent for the protection of hydroxyl groups or as a precursor to other functionalized organosilicon compounds.
• Agrochemical Research: Used in the synthesis of novel pesticide and herbicide candidates that incorporate silicon for enhanced stability or bioavailability.
• Polymer & Material Science: Employed in the modification of polymer surfaces or as a monomer component for creating silicon-containing specialty polymers.
• Cross-coupling & Catalysis: Serves as a reagent in palladium-catalyzed cross-coupling reactions to construct carbon-silicon bonds.
• Academic & Contract Research: A valuable tool for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	n-Trimethylsilylmethyl-n-Nitrosourea
CAS No.	39482-21-8
Molecular Formula	C6H15N3O2Si
Molecular Weight	189.29 g/mol
Synonyms	1-[(Trimethylsilyl)methyl]-1-nitrosourea; N-(Trimethylsilylmethyl)-N-nitrosourea; Trimethylsilylmethyl Nitrosourea; TMS-Methyl Nitrosourea; NSC 163049; Urea, N-methyl-N-nitroso-N'-(trimethylsilylmethyl)-; N-Nitroso-N-(trimethylsilylmethyl)urea
EINECS	Contact for details

Quality Control

Our n-Trimethylsilylmethyl-n-Nitrosourea is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and moisture content. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.