Description

(1R,2R,3R,4'Aα,7'β,9'Aβ)-3-Acetoxymethylhexahydro-3-Methyl-8'-Methylene-1',9'-Dioxospiro[Cyclohexane-1,4'(3'H)-[1H-7,9A]Methanocyclohepta[C]Pyran]-2-Carbaldehyde is a complex, high-purity spirocyclic organic compound with a defined stereochemistry. This compound is a critical advanced pharmaceutical intermediate or reference standard for research and development in medicinal chemistry. It is essential for organizations engaged in the synthesis of novel therapeutic agents, particularly those targeting complex biological pathways where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates, especially in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a precise molecular scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Used in universities and research institutes for studying novel organic reactions and synthetic methodologies.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and cellular studies due to its reactive aldehyde and ester functional groups.

Basic Information

Product Name	(1R,2R,3R,4'Aα,7'β,9'Aβ)-3-Acetoxymethylhexahydro-3-Methyl-8'-Methylene-1',9'-Dioxospiro[Cyclohexane-1,4'(3'H)-[1H-7,9A]Methanocyclohepta[C]Pyran]-2-Carbaldehyde
CAS No.	39388-60-8
Molecular Formula	C21H26O6
Molecular Weight	374.43 g/mol
Synonyms	3-Acetoxymethyl-3-methyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde; Spiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde, 3-(acetyloxy)methylhexahydro-3-methyl-8'-methylene-1',9'-dioxo-, (1R,2R,3R,4'a,7'β,9'aβ)-; (1R,2R,3R,4'a,7'β,9'aβ)-3-(Acetyloxy)methylhexahydro-3-methyl-8'-methylene-1',9'-dioxospiro[cyclohexane-1,4'(3'H)-[1H-7,9a]methanocyclohepta[c]pyran]-2-carbaldehyde; CAS 39388-60-8
EINECS	Contact for details

Quality Control

Our (1R,2R,3R,4'Aα,7'β,9'Aβ)-3-Acetoxymethylhexahydro-3-Methyl-8'-Methylene-1',9'-Dioxospiro[Cyclohexane-1,4'(3'H)-[1H-7,9A]Methanocyclohepta[C]Pyran]-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, typically including data from HPLC, NMR, and mass spectrometry. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. Keep container tightly sealed in a dry, well-ventilated place. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.