Description

(R)-Amino-Phenyl-Acetic Acid Ethyl Ester is a high-purity chiral building block essential for the synthesis of enantiomerically pure pharmaceuticals and fine chemicals. Its value lies in providing the critical (R)-configured α-amino acid ester moiety, which is a key structural component in many active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drugs, catalysts, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the production of antibiotics, ACE inhibitors, and other enantiopure drugs.
• Peptide Synthesis: Used in the preparation of protected amino acid derivatives for solid-phase and solution-phase peptide chemistry.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in stereoselective transformations.
• Agrochemical Research: Employed in the synthesis of chiral active ingredients for herbicides and pesticides.
• Fine Chemical Production: A building block for flavors, fragrances, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & R&D: Used in medicinal chemistry research and process development for new chemical entities.

Basic Information

Product Name	(R)-Amino-Phenyl-Acetic Acid Ethyl Ester
CAS No.	39251-40-6
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-2-Amino-2-phenylacetic acid ethyl ester; Ethyl (R)-2-amino-2-phenylacetate; D-α-Aminophenylacetic acid ethyl ester; (R)-Ethyl 2-amino-2-phenylacetate; (R)-Ethyl phenylglycinate; (R)-Ethyl α-aminophenylacetate; (R)-Ethyl 2-amino-2-phenylacetate; D-Phenylglycine ethyl ester
EINECS	Contact for details

Quality Control

Our (R)-Amino-Phenyl-Acetic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed HPLC/Chiral HPLC data are provided to guarantee consistent quality and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.