Description

Corey Pg-Lactone Diol is a high-value chiral building block and synthetic intermediate of significant importance in organic synthesis. Its unique lactone-diol structure makes it a versatile precursor for the construction of complex molecules, particularly in the pharmaceutical and fine chemical industries. This compound is primarily sought after by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), prostaglandin analogs, and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of prostaglandins and their analogs, which are crucial for various therapeutic applications.
• Fine Chemical Synthesis: Used as a building block for creating complex, stereochemically defined molecules in research and development.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric reactions to introduce specific stereocenters.
• Academic & Industrial R&D: Serves as a valuable starting material for methodological studies and the discovery of new chemical entities.
• Chemical Biology Probes: Potential use in the synthesis of labeled compounds or probes for studying biological pathways.

Basic Information

Product Name	Corey Pg-Lactone Diol
CAS No.	39182-59-7
Molecular Formula	C20H34O5
Molecular Weight	354.48 g/mol
Synonyms	(1S,5R,6R,7R)-7-[(1R,2R)-3,3-Ethylenedioxy-2-hydroxy-1-octyl]-6-[(E)-3-oxo-1-octenyl]-2-oxabicyclo[3.3.0]octan-3-one; Corey Lactone Diol; Corey Lactone PG; Prostaglandin F1α Lactone Diol; 11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid γ-Lactone, Corey Form; PGF1α Lactone Diol
EINECS	Contact for details

Quality Control

Our Corey Pg-Lactone Diol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.