Description

4-Azido-2,3,5,6-Tetrafluoropyridine is a high-value, multi-functional fluorinated heterocyclic building block. Its unique structure, featuring both an azido group and a perfluorinated pyridine ring, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in advanced material science and pharmaceutical development. It enables the synthesis of novel compounds with tailored properties for demanding applications.

Application

• Click Chemistry Reagent: The azido group makes it a prime candidate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, used to create complex polymers, dendrimers, and bioconjugates.
• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, where fluorine atoms are introduced to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of next-generation fluorinated pesticides and herbicides, leveraging fluorine's ability to increase lipophilicity and biological activity.
• Material Science Precursor: Employed in the synthesis of specialty fluoropolymers, liquid crystals, and electronic materials that require high thermal stability and chemical resistance.
• Ligand and Catalyst Development: Acts as a starting point for creating novel fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Energetic Materials Research: The combination of azide and fluorine groups makes it of interest in the study of high-energy-density materials.

Basic Information

Product Name	4-Azido-2,3,5,6-Tetrafluoropyridine
CAS No.	39066-42-7
Molecular Formula	C5HF4N4
Molecular Weight	196.08 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-azidopyridine; 4-Azidotetrafluoropyridine; Tetrafluoro-4-azidopyridine; 4-Azido-tetrafluoropyridine; 4-Azido-2,3,5,6-tetrafluoropyridine; Pyridine, 4-azido-2,3,5,6-tetrafluoro-
EINECS	Contact for details

Quality Control

Every batch of 4-Azido-2,3,5,6-Tetrafluoropyridine is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support applications requiring high-purity intermediates, from laboratory-scale research to pilot plant operations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.