Description

(4S)-4,5-Dihydro-4α-Hydroxy-5β-Methyl-3-[(Z)-Tetradecan-1-Ylidene]Furan-2(3H)-One is a high-purity, optically active lactone derivative with a specific stereochemistry and a long-chain alkylidene substituent. This compound is valued for its role as a key chiral intermediate or building block in advanced organic synthesis, particularly for pharmaceuticals and bioactive molecules. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific stereocenters and lipophilic chains into complex target structures.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially those requiring specific lactone motifs and stereochemistry.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its lipophilic chain can contribute to biological activity and membrane permeability.
• Fine Chemical Synthesis: Acts as a versatile precursor for creating complex natural product analogs, flavors, and fragrances.
• Material Science Research: Investigated as a monomer or functional additive for specialized polymers due to its reactive lactone ring and long alkyl chain.
• Biochemical Probes: Utilized in research to study enzyme mechanisms or as a template for designing enzyme inhibitors.
• Asymmetric Catalysis: May be employed as a substrate or ligand in the development of new asymmetric synthetic methodologies.

Basic Information

Product Name	(4S)-4,5-Dihydro-4α-Hydroxy-5β-Methyl-3-[(Z)-Tetradecan-1-Ylidene]Furan-2(3H)-One
CAS No.	38965-61-6
Molecular Formula	C19H34O3
Molecular Weight	310.47 g/mol
Synonyms	(4S)-4,5-Dihydro-4α-hydroxy-5β-methyl-3-[(Z)-1-tetradecylidene]-2(3H)-furanone; (Z)-3-(Tetradec-1-en-1-yl)-4,5-dihydro-4-hydroxy-5-methylfuran-2(3H)-one (4S,5R isomer); 4,5-Dihydro-4-hydroxy-5-methyl-3-[(1Z)-1-tetradecen-1-yl]-2(3H)-furanone, (4S,5R)-rel-; Lactone derivative CAS 38965-61-6; (4S,5R)-4-Hydroxy-5-methyl-3-[(Z)-tetradec-1-en-1-yl]dihydrofuran-2(3H)-one
EINECS	Contact for details

Quality Control

Our (4S)-4,5-Dihydro-4α-Hydroxy-5β-Methyl-3-[(Z)-Tetradecan-1-Ylidene]Furan-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.