Description

Deoxypodophyllic Acid is a key intermediate and reference standard in the synthesis of complex natural products and pharmaceutical agents. This compound is valued for its role as a precursor in the development of potent cytostatic and antiviral drugs, particularly those derived from podophyllotoxin. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical synthesis sectors, where precise chemical building blocks are required.

Application

• Pharmaceutical Intermediate: Critical precursor in the semi-synthesis of etoposide, teniposide, and other podophyllotoxin-derived chemotherapeutic agents.
• Biochemical Research: Used as a reference standard and starting material in studies of tubulin polymerization inhibition and topoisomerase II activity.
• Fine Chemical Synthesis: Serves as a sophisticated building block for the total synthesis of complex natural products and novel drug candidates.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Academic & Institutional Research: Utilized in university and institutional labs for investigating anticancer mechanisms and developing new therapeutic pathways.

Basic Information

Product Name	Deoxypodophyllic Acid
CAS No.	38943-33-8
Molecular Formula	C22H22O8
Molecular Weight	414.41 g/mol
Synonyms	Deoxypodophyllic Acid; 4'-Demethylepipodophyllotoxin; 4'-Demethyl-1-epipodophyllotoxin; NSC 334753; 5,8,8a,9-Tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; 4'-Demethylepipodophyllotoxin; 1-Epipodophyllotoxin, 4'-demethyl-
EINECS	Contact for details

Quality Control

Our Deoxypodophyllic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.