Description

19-Norpregn-4-En-20-Yn-3-One CAS NO 38673-42-6 is a high-purity steroidal intermediate of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of novel therapeutic agents, particularly in the field of endocrinology and hormone-related therapies. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of specialized steroid-based APIs and reference standards.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of advanced steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the discovery and development of new drug candidates targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroidal compounds.
• Academic Research: Utilized in university and institutional labs for studying steroid biochemistry and synthetic pathways.

Basic Information

Product Name	19-Norpregn-4-En-20-Yn-3-One
CAS No.	38673-42-6
Molecular Formula	C₂₁H₂₈O₂
Molecular Weight	312.45 g/mol
Synonyms	19-Norpregn-4-en-20-yn-3-one; 17α-Ethynyl-19-norandrost-4-en-3-one; 17α-Ethynyl-19-nortestosterone 3-enol ether precursor; 19-Nor-17α-pregn-4-en-20-yn-3-one; Norpregnene derivative; Steroid intermediate 38673-42-6; 17α-Ethynylestr-4-en-3-one (related structure)
EINECS	Contact for details

Quality Control

Our 19-Norpregn-4-En-20-Yn-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications for traceability and quality assurance, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.