Description

4-[4-[Bis(2-Chloroethyl)Amino]Phenoxy]-N,n-Bis(2-Chloroethyl)Aniline is a specialized nitrogen mustard derivative with a complex bifunctional structure, designed for targeted chemical reactivity. This compound matters as a critical intermediate in advanced pharmaceutical research, particularly in the development of targeted chemotherapeutic agents and antibody-drug conjugates (ADCs). It is needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking to develop novel therapeutic entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of experimental chemotherapeutic agents and targeted cancer therapies.
• Antibody-Drug Conjugate (ADC) Payload Synthesis: Serves as a precursor for constructing potent cytotoxin payloads that can be linked to monoclonal antibodies.
• Bioconjugation Research: Used in developing linker systems for attaching active molecules to proteins, peptides, or other biological carriers.
• Alkylating Agent Studies: Employed in biochemical and pharmacological research to study DNA cross-linking mechanisms and cell cycle effects.
• Fine Chemical Synthesis: Intermediate for creating complex organic molecules with specific biological activity in medicinal chemistry programs.
• Academic & Institutional Research: Utilized in university and government labs for investigating novel anti-cancer mechanisms and drug design.

Basic Information

Item	Details
Product Name	4-[4-[Bis(2-Chloroethyl)Amino]Phenoxy]-N,n-Bis(2-Chloroethyl)Aniline
CAS No.	38636-40-7
Molecular Formula	C22H28Cl4N2O
Molecular Weight	478.28 g/mol
Synonyms	NSC 338720; 1-[4-[4-[Bis(2-chloroethyl)amino]phenoxy]phenyl]-N,N-bis(2-chloroethyl)amine; Phenesterine; 4'-[4-[Bis(2-chloroethyl)amino]phenoxy]-N,N-bis(2-chloroethyl)[1,1'-biphenyl]-4-amine; 4-[p-[Bis(2-chloroethyl)amino]phenoxy]-N,N-bis(2-chloroethyl)aniline; CB 3049
EINECS	Contact for details

Quality Control

Every batch of our 4-[4-[Bis(2-Chloroethyl)Amino]Phenoxy]-N,n-Bis(2-Chloroethyl)Aniline is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity and purity. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.