Description

Methyl 5-Doxyl-Stearate is a spin-labeled fatty acid ester, specifically a stearic acid derivative bearing a stable nitroxide radical (doxyl group) at the 5-position. This compound matters as a crucial spin probe and label in electron paramagnetic resonance (EPR) spectroscopy for studying membrane fluidity, protein-lipid interactions, and molecular dynamics in biophysical and materials research. Researchers and formulators in advanced life sciences, polymer science, and analytical chemistry need it to investigate structural and dynamic properties at the molecular level.

Application

• As a spin probe in EPR/ESR spectroscopy for analyzing membrane fluidity and phase transitions in lipid bilayers and model membranes.
• Used in biophysical research to study protein-lipid interactions and the dynamics of biomolecules within lipid environments.
• As a molecular label for investigating polymer chain mobility, free volume, and microstructure in advanced materials science.
• Employed in the development and calibration of diagnostic assays and sensors that utilize nitroxide radical chemistry.
• Utilized in oxidative stress studies to monitor radical processes and antioxidant efficacy.
• Serves as a reference standard or intermediate in the synthesis of more complex spin-labeled compounds for specialized research applications.

Basic Information

Product Name	Methyl 5-Doxyl-Stearate
CAS No.	38568-24-0
Molecular Formula	C24H46NO4
Molecular Weight	412.63 g/mol
Synonyms	Methyl 5-Doxylstearate; Methyl 5-(1-Oxyl-2,2,6,6-tetramethyl-4-piperidinyl)octadecanoate; 5-DOXYL-stearic acid methyl ester; Methyl 5-(2,2,6,6-tetramethyl-1-oxyl-4-piperidinyl)octadecanoate; 5-SASL; 5-Doxyl methyl stearate; Methyl 5-(TEMPO)stearate; Spin-labeled methyl stearate
EINECS	Contact for details

Quality Control

Our Methyl 5-Doxyl-Stearate is produced and handled under strict quality protocols to ensure high purity and radical stability, critical for sensitive spectroscopic applications. Each batch undergoes rigorous analytical testing, including EPR for radical content and HPLC for chemical purity, to ensure consistency and performance. A comprehensive Certificate of Analysis (COA) detailing assay, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as recommended on the label or COA to minimize oxidation and degradation of the nitroxide radical. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange waxy solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Radical Content (EPR)	≥ 90% of theoretical
Melting Point	Contact for details
Solubility	Soluble in common organic solvents (e.g., chloroform, ethanol, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.