Description

Bis[p-[Bis(2-Chloroethyl)Amino]Phenylacetic Acid]2-Hydroxy-1,3-Propanediyl Ester is a specialized nitrogen mustard derivative with a bifunctional ester linkage. This compound is valued for its role as a key chemical intermediate in the research and development of targeted therapeutic agents, particularly in oncology. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel prodrugs and cytostatic compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of experimental anticancer prodrugs and targeted cytostatic agents.
• Bioconjugation Research: Used in the development of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its reactive ester and nitrogen mustard groups.
• Medicinal Chemistry: A key precursor for structure-activity relationship (SAR) studies aimed at optimizing the potency and selectivity of alkylating agents.
• Biochemical Research: Employed in studies investigating DNA alkylation mechanisms and the design of novel chemotherapeutic candidates.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.

Basic Information

Product Name	Bis[p-[Bis(2-Chloroethyl)Amino]Phenylacetic Acid]2-Hydroxy-1,3-Propanediyl Ester
CAS No.	38358-06-4
Molecular Formula	C31H40Cl4N2O6
Molecular Weight	662.47 g/mol
Synonyms	1,3-Propanediol, 2-hydroxy-, bis[4-[bis(2-chloroethyl)amino]phenylacetate]; 2-Hydroxy-1,3-propanediyl bis[4-[bis(2-chloroethyl)amino]phenylacetate]; Bis(4-[bis(2-chloroethyl)amino]phenylacetic acid) 2-hydroxy-1,3-propanediyl ester; Nitrogen mustard phenylacetic acid glycerol ester; Glycerol 1,3-bis(4-[bis(2-chloroethyl)amino]phenylacetate)
EINECS	Contact for details

Quality Control

Our Bis[p-[Bis(2-Chloroethyl)Amino]Phenylacetic Acid]2-Hydroxy-1,3-Propanediyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.