Description

(-)-Dimethyl 2,3-o-Benzylidene-L-Tartrate is a high-purity chiral building block and protecting group reagent derived from L-tartaric acid. This compound is valued for its role in asymmetric synthesis, enabling the construction of complex molecules with precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and advanced intermediates.

Application

• Asymmetric Synthesis: A key chiral auxiliary and precursor for synthesizing enantiomerically pure compounds.
• Pharmaceutical Intermediates: Used in the production of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Development: Employed in creating chiral pesticides and herbicides with enhanced efficacy and selectivity.
• Fine Chemical Manufacturing: Serves as a building block for specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable reagent for methodological development in organic and medicinal chemistry.
• Protecting Group Chemistry: The benzylidene acetal group protects diols, which can be selectively deprotected under mild conditions.

Basic Information

Product Name	(-)-Dimethyl 2,3-o-Benzylidene-L-Tartrate
CAS No.	38270-72-3
Molecular Formula	C13H14O6
Molecular Weight	266.25 g/mol
Synonyms	Dimethyl (4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-dicarboxylate; L-(-)-Dimethyl 2,3-O-Benzylidenetartrate; (4R,5R)-4,5-Bis(methoxycarbonyl)-2-phenyl-1,3-dioxolane; Benzylidene-L-tartaric Acid Dimethyl Ester; (-)-Dimethyl O-Benzylidene-L-tartrate; (R,R)-(-)-Dimethyl 2,3-O-Benzylidenetartrate
EINECS	Contact for details

Quality Control

Our (-)-Dimethyl 2,3-o-Benzylidene-L-Tartrate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific rotation are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Specific Rotation [α]D20	-80° to -85° (c=1 in CHCl3)
Melting Point	78°C - 82°C
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.