Description

(E)-3-(4-Hydroxyphenyl)-1-Phenyl-Prop-2-En-1-One is a high-purity, light-sensitive chalcone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a versatile and critical building block for the development of novel bioactive molecules, offering a defined structural scaffold for chemical modification. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and metabolic disorders.
• Organic Light-Emitting Diode (OLED) Materials: Used in the research and development of organic electronic materials due to its conjugated molecular structure.
• UV Absorber & Photostabilizer Research: Investigated for its potential application in polymer stabilization and sunscreen formulations owing to its chromophore.
• Agrochemical Synthesis: Serves as an intermediate for developing new generation pesticides and herbicides.
• Flavonoid & Natural Product Analog Synthesis: A fundamental scaffold for creating synthetic analogs of biologically active natural products like flavonoids.
• Chemical Biology Probe Development: Utilized in crafting molecular probes to study biological pathways and protein functions.
• Academic & Industrial R&D: A standard reagent for methodological studies in organic chemistry, including cross-coupling and cyclization reactions.

Basic Information

Product Name	(E)-3-(4-Hydroxyphenyl)-1-Phenyl-Prop-2-En-1-One
CAS No.	38239-55-3
Molecular Formula	C15H12O2
Molecular Weight	224.26 g/mol
Synonyms	4-Hydroxychalcone; (E)-1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one; 3-(4-Hydroxyphenyl)-1-phenyl-2-propen-1-one; p-Hydroxychalcone; Chalcone, 4'-hydroxy-; NSC 407292; 2-Propen-1-one, 3-(4-hydroxyphenyl)-1-phenyl-, (E)-; 4'-Hydroxychalcone
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Hydroxyphenyl)-1-Phenyl-Prop-2-En-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	168°C - 172°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.