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4'-Methoxyphenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside CAS NO 38229-72-0


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CAS No.:38229-72-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4'-Methoxyphenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is a key protected glycoside derivative, specifically an acetylated N-acetylglucosamine (GlcNAc) analog with a methoxyphenyl aglycone. This compound is a critical advanced pharmaceutical intermediate and a versatile building block in synthetic carbohydrate chemistry. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and biochemical tools.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex glycoconjugates, glycopeptide antibiotics, and glycosidase inhibitors.
  • Glycobiology Research: Used as a protected donor or acceptor substrate for enzymatic or chemical glycosylation studies to understand carbohydrate-protein interactions.
  • Oligosaccharide Synthesis: Serves as a key building block for the stepwise chemical synthesis of defined oligosaccharides and glycans.
  • Probe and Diagnostic Development: Utilized in creating labeled carbohydrate probes for imaging, biosensing, and diagnostic assay development.
  • Chemical Biology Tool: Employed to prepare neoglycoconjugates for studying cell surface recognition processes and immune responses.
  • Fine Chemical Synthesis: Acts as a specialized starting material for synthesizing high-value chiral compounds and complex natural product analogs.

Basic Information

Item Detail
Product Name 4'-Methoxyphenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside
CAS No. 38229-72-0
Molecular Formula C21H27NO10
Molecular Weight 453.44 g/mol
Synonyms p-Methoxyphenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; 4-Methoxyphenyl N-acetyl-β-D-glucosaminide triacetate; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose 4-methoxyphenyl glycoside; GlcNAc(β1-OR) triacetate (R=4-methoxyphenyl); N-Acetyl-β-D-glucosaminide, p-methoxyphenyl, peracetylated; 38229-72-0; β-D-Glucopyranoside, 4-methoxyphenyl 2-(acetylamino)-2-deoxy-, 3,4,6-triacetate
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Quality Control

Our 4'-Methoxyphenyl-2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and specific optical rotation measurement, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Specific Optical Rotation [α]²⁰D -30° to -40° (c=1 in CHCl₃)
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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