Description

4-(N,n-Bis(2-Chloroethyl)Amino)Phenyl o-β-D-Glucopyranosiduronic Acid is a specialized chemical intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key building block in the synthesis of targeted therapeutic agents, particularly in the field of oncology. Pharmaceutical manufacturers and advanced research institutions require this high-purity intermediate to develop novel prodrugs and antibody-drug conjugates (ADCs). Its precise structure enables the creation of sophisticated drug delivery systems designed for enhanced efficacy and reduced side effects.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted chemotherapeutic prodrugs and antibody-drug conjugates (ADCs).
• Oncology Research: Used in R&D for developing novel cancer therapies that leverage selective drug activation mechanisms.
• Prodrug Synthesis: Serves as a glycosylated carrier moiety designed for enzymatic activation in specific tissue environments.
• Bioconjugation Chemistry: Employed in the design and construction of complex molecules for targeted drug delivery platforms.
• Biochemical Research: Utilized in studies investigating drug metabolism and the design of enzyme-activated therapeutic agents.
• Pre-clinical Development: Supports the manufacturing of compounds for pharmacological and toxicological evaluation.

Basic Information

Item	Details
Product Name	4-(N,n-Bis(2-Chloroethyl)Amino)Phenyl o-β-D-Glucopyranosiduronic Acid
CAS No.	38099-65-9
Molecular Formula	C18H24Cl2N2O8
Molecular Weight	467.30 g/mol
Synonyms	Phenyl N,N-bis(2-chloroethyl)carbamate glucuronide; 4-[Bis(2-chloroethyl)amino]phenyl β-D-glucopyranosiduronic acid; Phenesterin glucuronide; NSC 104469; Glucuronide conjugate of phenesterin; Mustard phenol glucuronide; β-Glucuronidase-sensitive prodrug intermediate
EINECS	Contact for details

Quality Control

Our 4-(N,n-Bis(2-Chloroethyl)Amino)Phenyl o-β-D-Glucopyranosiduronic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency for research and development purposes. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. While not intended for human use as supplied, production follows principles of current Good Manufacturing Practice (cGMP) where applicable for advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.