Description

(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Malonic Acid Dibenzyl Ester is a specialized organic intermediate featuring a phthalimide-protected malonate structure. This compound matters for its role as a versatile building block in the synthesis of complex molecules, offering controlled reactivity for the introduction of malonic acid derivatives. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and advanced materials sectors for constructing active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Mimetics & Conjugate Chemistry: Used to introduce malonate-based linkers or spacers in the design of peptide analogs and bioconjugates.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and other C-C bond-forming transformations in fine chemical production.
• Agrochemical Research: Utilized as a precursor in the development of novel herbicides and plant growth regulators.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing phthalimide-based colorants and functional dyes.

Basic Information

Product Name	(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Malonic Acid Dibenzyl Ester
CAS No.	38068-70-1
Molecular Formula	C25H19NO6
Molecular Weight	429.42 g/mol
Synonyms	Dibenzyl (1,3-Dioxoisoindolin-2-yl)malonate; Dibenzyl 2-(1,3-Dioxoisoindolin-2-yl)malonate; N-Phthalimidomalonic Acid Dibenzyl Ester; Phthalimidomalonic Acid Dibenzyl Ester; 2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)malonic Acid Dibenzyl Ester; DBDA; Dibenzyl Phthalimidomalonate
EINECS	Contact for details

Quality Control

Our (1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)Malonic Acid Dibenzyl Ester undergoes rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We maintain strict in-process controls and final release criteria, including identity confirmation and purity verification. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be conducted under conditions that minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.