Description

(Z)-2-Methyl-2-Butenoic Acid [(3R)-2,3,8,8Aβ-Tetrahydro-5-Hydroxy-3,6,8,8-Tetramethyl-4,9-Dioxo-3Aα,7-Methano-1H-Azulen-7β(4H)-Yl] Ester is a high-purity, complex sesquiterpene derivative ester with significant value in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral intermediate for the development of novel therapeutic agents and fine chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in anti-inflammatory and anti-infective research.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce complex, polycyclic frameworks into target molecules.
• Natural Product Analog Synthesis: Serves as a precursor for synthesizing analogs of natural products with sesquiterpene backbones for biological evaluation.
• Agrochemical Research: Intermediate in the development of new, high-value active ingredients with specific biological activity.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Institutional Research: Valuable reference standard and reagent for studies in organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Item	Details
Product Name	(Z)-2-Methyl-2-Butenoic Acid [(3R)-2,3,8,8Aβ-Tetrahydro-5-Hydroxy-3,6,8,8-Tetramethyl-4,9-Dioxo-3Aα,7-Methano-1H-Azulen-7β(4H)-Yl] Ester
CAS No.	38044-08-5
Molecular Formula	C₂₀H₂₈O₅
Molecular Weight	348.43 g/mol
Synonyms	2-Methyl-2-butenoic acid (3R)-2,3,8,8a-tetrahydro-5-hydroxy-3,6,8,8-tetramethyl-4,9-dioxo-3a,7-methano-1H-azulen-7(4H)-yl ester; (Z)-Tiglic Acid Guaiazulene Ester Derivative; 7β-Hydroxy-4α,8β-dimethyl-1-oxo-1,4,4a,5,6,7,8,8a-octahydro-2-naphthalenyl (2Z)-2-methyl-2-butenoate (related structural name); Sesquiterpene Ester 38044-08-5; Complex Guaiazulene Derivative Ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Quality is verified through modern analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.