Description

8-Benzyl-1,4-Dioxa-8-Azaspiro[4.5]Decane is a versatile nitrogen- and oxygen-containing heterocyclic compound, specifically a spirocyclic acetal, that serves as a crucial synthetic intermediate and building block in advanced organic synthesis. Its unique spirocyclic structure, featuring a benzyl-protected nitrogen, makes it a valuable precursor for constructing complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) or requiring complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Employed in the multistep synthesis of high-value specialty chemicals, dyes, and functional polymers.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new spirocyclization and protection/deprotection strategies.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.

Basic Information

Product Name	8-Benzyl-1,4-Dioxa-8-Azaspiro[4.5]Decane
CAS No.	37943-54-7
Molecular Formula	C14H19NO2
Molecular Weight	233.31 g/mol
Synonyms	8-Benzyl-1,4-dioxa-8-azaspiro[4.5]decane; 1,4-Dioxa-8-azaspiro[4.5]decane, 8-benzyl-; 8-Benzyl-8-aza-1,4-dioxaspiro[4.5]decane; N-Benzyl-1,4-dioxa-8-azaspiro[4.5]decane; 8-Benzyl-8-aza-1,4-dioxaspiro[4.5]decane; N-Benzyl-4,4-ethylenedioxy-1-azacyclopentane; 4,4-Ethylenedioxy-1-(phenylmethyl)azacyclopentane; 1-Benzyl-4,4-ethylenedioxyazacyclopentane
EINECS	Contact for details

Quality Control

Our 8-Benzyl-1,4-Dioxa-8-Azaspiro[4.5]Decane is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure (1H & 13C NMR)
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.