Description

Ethyl 4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs, particularly for research into kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrazolopyridine core structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing novel molecular architectures in medicinal chemistry.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate
CAS No.	37801-57-3
Molecular Formula	C11H10ClN3O2
Molecular Weight	251.67 g/mol
Synonyms	4-Chloro-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester; Ethyl 4-chloro-1-methylpyrazolo[3,4-b]pyridine-5-carboxylate; 1-Methyl-4-chloro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester; 37801-57-3; Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 4-chloro-1-methyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-1-Methyl-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.