Description

(S)-Methyl 2-Amino-2-Phenylacetate CAS NO 37760-98-8 is a high-purity chiral building block essential for the synthesis of optically active pharmaceutical intermediates. Its enantiomeric purity is critical for developing active pharmaceutical ingredients (APIs) with the desired biological activity and safety profile. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of various APIs, including antibiotics, enzyme inhibitors, and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Peptidomimetics Research: Serves as a protected amino acid derivative for constructing peptide analogs and mimetics in medicinal chemistry.
• Catalyst and Ligand Preparation: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric transformations.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes involving stereoselective reactions.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiopurity.

Basic Information

Product Name	(S)-Methyl 2-Amino-2-Phenylacetate
CAS No.	37760-98-8
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(S)-Methyl 2-Amino-2-phenylacetate; (S)-Methyl 2-Amino-2-phenylacetate; (S)-Methyl phenylglycinate; (S)-Methyl α-aminophenylacetate; (S)-Methyl 2-Phenylglycinate; L-Methyl phenylglycinate; Methyl (S)-2-amino-2-phenylacetate; Methyl (S)-phenylglycinate
EINECS	Contact for details

Quality Control

Our (S)-Methyl 2-Amino-2-Phenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request, supporting compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.