Description

Ethyl 3-Phenyl-1,2,4-Oxadiazole-5-Carboxylate is a versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the 1,2,4-oxadiazole ring, a privileged scaffold known for imparting favorable physicochemical and biological properties to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, serving as a key intermediate for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the 1,2,4-oxadiazole moiety.
• Material Science: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes and tags for studying biological processes and enzyme functions.
• Coordination Chemistry: Acts as a ligand or precursor for metal-organic frameworks (MOFs) and catalytic complexes.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Item	Details
Product Name	Ethyl 3-Phenyl-1,2,4-Oxadiazole-5-Carboxylate
CAS No.	37760-54-6
Molecular Formula	C11H10N2O3
Molecular Weight	218.21 g/mol
Synonyms	Ethyl 3-phenyl-1,2,4-oxadiazole-5-carboxylate; 5-Ethoxycarbonyl-3-phenyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole-5-carboxylic acid, 3-phenyl-, ethyl ester; Ethyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate (isomer); 3-Phenyl-1,2,4-oxadiazole-5-carboxylic acid ethyl ester; NSC 163044
EINECS	Contact for details

Quality Control

Our Ethyl 3-Phenyl-1,2,4-Oxadiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. For custom synthesis or specific purity grades (e.g., >98%, >99%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.