Description

L-Serine, 1-Methylethyl Ester, Hydrochloride is a protected derivative of the essential amino acid L-serine, specifically formulated as its hydrochloride salt for enhanced stability and handling. This compound is a critical chiral building block in the synthesis of complex pharmaceuticals and bioactive peptides, offering precise control over stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, antiviral drugs, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate serine residues while protecting the side-chain hydroxyl group.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Agrochemical Development: Potential intermediate in the research and development of new, targeted agrochemicals.

Basic Information

Product Name	L-Serine, 1-Methylethyl Ester, Hydrochloride
CAS No.	37592-53-3
Molecular Formula	C6H14ClNO3
Molecular Weight	183.63 g/mol
Synonyms	L-Serine isopropyl ester hydrochloride; Isopropyl L-serinate hydrochloride; (S)-2-Amino-3-hydroxypropanoic acid 1-methylethyl ester hydrochloride; Serine isopropylester HCl; O-Isopropyl-L-serine hydrochloride; L-Serine O-isopropyl ester hydrochloride; (S)-Serine isopropyl ester hydrochloride; L-Serine isopropylester hydrochloride
EINECS	Contact for details

Quality Control

Our L-Serine, 1-Methylethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity, correct stereochemistry, and consistency. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing parameters such as assay, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.