Description

Tris(N n-Bis(Trimethylsilyl)Amide)Scan is a highly specialized organosilicon reagent, primarily used as a powerful silylating agent and a strong, non-nucleophilic base. This compound is critical for advanced synthetic chemistry, enabling the protection of sensitive functional groups and facilitating challenging deprotonation reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity reagents for complex synthesis and process development.

Application

• Silylation Reagent: For the protection of hydroxyl, amine, and thiol groups in complex multi-step organic synthesis, particularly in pharmaceutical intermediate production.
• Strong Non-Nucleophilic Base: Used in deprotonation reactions where traditional bases like LDA are unsuitable, especially in the synthesis of sensitive or sterically hindered compounds.
• Precursor for Metal-Amide Complexes: Serves as a ligand or precursor in the preparation of catalysts for polymerization and other organometallic reactions.
• Silicon Nitride (Si3N4) CVD Precursor: Employed in chemical vapor deposition processes for the production of high-performance ceramic coatings and electronic materials.
• Reagent in Peptide Synthesis: Used for the temporary protection of amino acids, preventing unwanted side reactions during coupling steps.
• Research & Development: A key tool in academic and industrial R&D labs for developing new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	Tris(N n-Bis(Trimethylsilyl)Amide)Scan
CAS No.	37512-28-0
Molecular Formula	C18H57N4Si9
Molecular Weight	599.48 g/mol
Synonyms	Tris[bis(trimethylsilyl)amino]silane; Tris(N,N-bis(trimethylsilyl)amide)silane; Silicon tris(hexamethyldisilazide); Tris(hexamethyldisilazido)silane; Si(HMDS)3; Tris(1,1,1,3,3,3-hexamethyldisilazanyl)silane; Silicon tris(di(trimethylsilyl)amide)
EINECS	Contact for details

Quality Control

Our Tris(N n-Bis(Trimethylsilyl)Amide)Scan is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) documenting purity (typically ≥95% by NMR or GC), physical characteristics, and moisture content are provided with every shipment. We support compliance with cGMP and ISO 9001 standards for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C. Keep the container tightly sealed in a dry inert-gas atmosphere when not in use. Handle and store under dry, oxygen-free conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (NMR)	≥ 95.0%
Purity (GC)	≥ 95.0%
Moisture (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.